Input sequence

Protein name Ryanodine receptor 2
Organism Mus musculus Length 4966
Disorder content 13.3% ProS content 7.1%
IDEAL NA UniProt E9Q401

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 4966 1-9 10-84 85-102 103-381 382-390 391-467 468-481 482-734 735-742 743-961 962-971 972-1068 1069-1074 1075-1080 1081-1332 1333-1414 1415-1493 1494-1502 1503-1746 1747-1751 1752-1857 1858-1887 1888-2010 2011-2052 2053-2352 2353-2375 2376-2795 2796-2814 2815-2907 2908-2914 2915-2946 2947-2952 2953-2986 2987-2989 2990-2997 2998-3187 3188-3197 3198-3342 3343-3347 3348-3429 3430-3461 3462-3642 3643-3658 3659-3697 3698-3722 3723-3822 3823-3829 3830-4202 4203-4240 4241-4244 4245-4277 4278-4300 4301-4307 4308-4318 4319-4415 4416-4443 4444-4479 4480-4523 4524-4554 4555-4675 4676-4687 4688-4691 4692-4962 4963-4966 10-84 103-381 391-467 482-734 743-961 972-1068 1081-1332 1415-1493 1503-1746 1752-1857 1888-2010 2053-2352 2376-2795 2815-2907 2915-2946 2953-2986 2998-3187 3198-3342 3348-3429 3462-3642 3659-3697 3723-3822 3830-4202 4241-4244 4278-4300 4308-4318 4416-4443 4480-4523 4555-4675 4692-4962 1-9 85-102 382-390 468-481 735-742 962-971 1075-1080 1333-1414 1494-1502 1747-1751 1858-1887 2011-2052 2353-2375 2796-2814 2908-2914 2947-2952 2990-2997 3188-3197 3343-3347 3430-3461 3643-3658 3698-3722 3823-3829 4203-4240 4245-4277 4301-4307 4319-4415 4444-4479 4524-4554 4676-4687 4963-4966 1-9 95-102 468-481 735-742 962-971 1075-1080 1333-1360 1369-1377 1387-1400 1405-1414 1747-1751 1877-1887 2023-2038 2353-2375 2800-2807 2908-2914 2947-2952 2990-2997 3192-3197 3343-3347 3454-3461 3643-3646 3698-3701 3711-3722 3823-3829 4215-4235 4245-4277 4301-4307 4331-4339 4361-4365 4376-4401 4676-4679 4963-4966 10-544 660-1277 1400-1563 2700-2904 3580-3606 9-544 660-1356 2699-2904 1087-1672 300-995 2581-2790 2808-3304 4484-4656 3580-3606 4031-4084 4379-4598 13-214 3829-3954 2700-2790 861-947 976-1068 2820-2904 456-648 2122-2324 1099-1207 753-800 235-372 226-406 451-655 670-808 861-955 975-1069 1098-1221 1423-1562 2120-2331 2699-2793 2819-2907 3464-3959 4332-4598 4689-4865 230-396 730-1023 3298-3449 2707-2949 2518-2600 1037-1233 1396-1568 3957-4083 230-405 4031-4088 701-719 1643-1653 1872-1891 2372-2379 2416-2426 2497-2510 2853-2865 3700-3720 4218-4227 4256-4273 4309-4317 4339-4350 4359-4377 4413-4457 4766-4784 4843-4861 4416-4443 4278-4300 4497-4516 4570-4592 4709-4731 4766-4788 4847-4866 4jkqA(1-499) 0.0 91.21% 4uweA(583-1109) 0.0 55.73% 4uweA(1043-1181) 9e-40 53.05% 4etvA(1-183) 1e-82 87.8% 2bcxB(1-27) 7e-07 88.89% 4uweA(1-523) 0.0 67.22% 4uweA(583-1160) 0.0 51.34% 4uweA(1792-1973) 2e-114 57.77% 4uweA(584-1169) 5e-73 18.14% 4uweA(591-1172) 1e-44 17.47% 4uweA(1806-1973) 3e-40 22.17% 4uweA(707-1166) 5e-32 15.11% 1k8kE(2-171) 6e-08 14.45% 2bcxB(1-27) 7e-08 88.89% 2fceA(11-65) 2e-06 27.27% PF06459(47-270) 2e-37 44.3% PF08709(5-218) 4e-33 43.18% PF08454(4-114) 5e-31 56.35% PF02026(2-92) 8e-26 54.95% PF02026(1-87) 6e-23 55.17% PF02026(2-94) 3e-21 45.16% PF02026(2-92) 8e-13 43.96% PF01365(5-194) 2e-24 39.59% PF01365(2-182) 2e-23 34.29% PF00622(2-107) 6e-05 30.36% PF00622(66-113) 0.001 41.67% PF02815(1-130) 8e-05 24.46% PF02815 5e-82 283.1% PF01365 1.3e-96 331.5% PF00622 1.4e-36 132.1% PF02026 3e-61 214.1% PF02026 8.3e-63 219.2% PF00622 4.2e-43 153.8% PF00622 3.4e-34 124.2% PF01365 3.7e-84 290.2% PF02026 7.4e-65 226.0% PF02026 5.8e-32 116.8% PF08454 7.8e-273 916.9% PF06459 1.5e-137 467.5% PF00520 1.3e-07 35.8% 1n4kA2(1-132) 1e-34 17.26% 1a8iA(235-536) 8e-22 13.17% 1ak6A(21-172) 2e-20 15.0% 1b7eA(1-249) 3e-20 6.43% 2i76A1(10-102) 7e-20 12.9% 2fnjA1(10-214) 2e-15 12.39% 2fbeA1(15-182) 3e-06 11.48% 1ij5A(100-230) 3e-10 17.39% b.42.6 6.2e-71 236.1% a.39.1 2.1e-11 35.8%

Sequence

MADAGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPP
DLSICTFVLEQSLSVRALQEMLANTVEKSEGQVDVEKWKFMMKTAQGGGHRTLLYGHAIL
LRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDD
LILVSVSSERYLHLSYGNSSWHVDAAFQQTLWSVAPISSGSEAAQGYLIGGDVLRLLHGH
MDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHV
TTGKYLSLMEDKNLLLMDKEKADVKSTAFAFRSSKEKLDVGVRKEVDGMGTSEIKYGDSI
CYIQHVDTGLWLTYQAVDVKSARMGSIQRKAIMHHEGHMDDGLNLSRSQHEESRTARVIR
STVFLFNRFIRGLDALSKKVKLPTIDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLR
ALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAGREAGESWKSILNSLYELLAAL
IRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISL
LDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIF
LGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGD
DLFSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFE
NFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAACYEAVLPKEKLKVEHSREY
KQERTYTRDLLGPTVSLTQAAFTPVPVDTSQIVLPPHLERIRERLAENIHELWVMNKIEL
GWQYGPVRDDNKRQHPCLVEFCKLPEQERNYNLQMSLETLKTLLALGCHVGIADEHAEEK
VKKMKLPKNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGI
QQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYHLEAPDQDHASRAEVCSG
TGERFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDLELGSDDRAFAFDGF
KAQRWHQGNEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVGDG
FIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQ
VPSNHEHIEVTRIDGTIDSSPCLKVTQKSFGSQNNNTDIMFYRLSMPIECAEVFSKSVAG
GLPGAGFYGPKNDLEDFDVDSDFEVLMKTAHGHLVPDRIDKDKETPKPEFNNHKDYAQEK
PSRLKQRFLLRRTKPDYSTGHSARLTEDVLADDRDDYEYLMQTSTYYYSVRIFPGQEPAN
VWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESMSPGQGR
NNSNGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGR
IKNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLV
QCLDPLQFMSLHIPEENRSVDILELTEQEELLQFHYHTLRLYSAVCALGNHRVAHALCSH
VDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETKSITLF
PDENKKHGLPGIGLSTSLRPRMRFSSPSFVSISNDCYQYSPEFPLDILKAKTIQMLTEAV
KEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFKEAAVPEE
EGGTPEKEISIEDAKLEGEEEAKGGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRHR
IEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTREFRSPPQEQINMLLNFKD
DKSECPCPEEIRDQLLDFHEDLMTHCGIELDEDGSLDGSNDLTIRGRLLSLVEKVTYLKK
KQAEKPVASDSRKCSSLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRA
LPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNL
MRALGMHETVMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYL
LENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQMLV
SKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGN
GLLAAMEEAIKIAEDPSRDGPSPTSGSSKTLDIEEEEDDTIHMGNAIMTFYAALIDLLGR
CAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGKVVEPDMSAGFC
PDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLC
TAVLPLLTRCAPLFAGTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQLR
PSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHLS
RKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEKQSSMDSEGNF
NPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKIQPLMKPYK
LLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQVSIDAAHGY
SPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKLELESKGGGNHPLLVPYDTLTAKE
KAKDREKAQDIFKFLQISGYVVSRGFKDLDLDTPSIEKRFAYSFLQQLIRYVDEAHQYIL
EFDGGSRSKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCTGGHASNKEK
EMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLDSVKSALRAFL
DNAAEDLEKTMENLKQGQFTHTRSQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGEDL
ILEDVQVSCYRILTSLYALGTSKSIYVERQRSALGECLAAFAGAFPIAFLETHLDKHNVY
SIYNTRSSRERAALSLPANVEDVCPNIPSLEKLMTEIIELAESGIRYTQMPYMMEVVLPM
LCSYMSRWWEHGPENHPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAV
FSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVVSEEDHLKAEARGDMSEAELLILDEFTT
LARDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFVV
QNEINNMSFLITDTKSKMSKAAISDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNIC
APGDQELIALAKNRFSLKDTEEEVRDIIRSNIHLQGKLEDPAIRWQMALYKDLPNRTEDP
SDPERTVERVLGIANVLFHLEQKSKYTGRGYFSLVEHPQRSKKAVWHKLLSKQRKRAVVA
CFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPGAELPEEDEAMKRV
DPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCHDEEDDDGEEEVKSFEEKEMEK
QKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDYL
KEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVLQDDEFTCDLFR
FLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDIIDEQ
GQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQD
SSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFL
KLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYE
EFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGS
AKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQ
LAAQISESDLNERLANKEESEKERPEEQAPRMGFFSLLTIQSALFALRYNVLTLVRMLSL
KSLKKQMKRMKKMTVKDMVLAFFSSYWSVFVTLLHFVASVCRGFFRIVSSLLLGGSLVEG
AKKIKVAELLANMPDPTQDEVRGDEEEGERKPLESALPSEDLTDLKELTEESDLLSDIFG
LDLKREGGQYKLIPHNPNAGLSDLMTNPVPVPEVQEKFQEQKAKEEKEEKEETKSEPEKA
EGEDGEKEEKAKDEKSKQKLRQLHTHRYGEPEVPESAFWKKIIAYQQKLLNYFARNFYNM
RMLALFVAFAINFILLFYKVSTSSVVEGKELPTRTSSDTAKVTNSLDSSPHRIIAVHYVL
EESSGYMEPTLRILAILHTIISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQP
SEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSD
AREKKKPKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAA
HLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDT
PDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAI
IQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFF
LMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN

Region:1-4966
Length:4966aa
Label:Full sequence
Reset:click