Input sequence

Protein name Voltage-dependent R-type calcium channel subunit alpha-1E
Organism Homo sapiens Length 2313
Disorder content 37.3% ProS content 19.1%
IDEAL NA UniProt Q15878

Prediction

Order Disorder ProS BLAST:PDB BLAST:PDB BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:PDB RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam RPS-BLAST:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam HMMER:Pfam RPS-BLAST:SCOP RPS-BLAST:SCOP RPS-BLAST:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP HMMER:SCOP SEG:LCR COILS:coiledCoil TMHMM:TMhelix 0 2313 1-58 59-400 401-447 448-453 454-733 734-744 745-748 749-771 772-801 802-1098 1099-1244 1245-1247 1248-1686 1687-1690 1691-1886 1887-2313 59-400 454-733 745-748 772-801 1099-1244 1248-1686 1691-1886 1-58 401-447 734-744 749-771 802-1098 1887-2313 1-23 48-58 401-447 734-744 749-751 764-771 802-854 884-906 965-977 1000-1060 1067-1079 1087-1098 1911-1922 1943-1954 2033-2039 2065-2082 2101-2138 2154-2162 2167-2173 2225-2235 2242-2264 2275-2286 2300-2313 358-402 1249-1276 1807-1882 1724-1817 358-402 1807-1884 1249-1276 1513-1722 131-350 1189-1383 525-701 126-350 510-702 1188-1422 1512-1722 1474-1588 472-582 85-202 12-359 381-711 1075-1431 1460-1766 224-240 507-522 592-620 716-721 762-776 806-821 834-848 911-927 932-947 1100-1125 1159-1172 1227-1244 1401-1419 2049-2065 2077-2090 2112-2128 2156-2170 2210-2225 2284-2294 373-400 699-733 1099-1126 90-109 129-151 158-180 221-243 296-318 328-350 476-498 503-525 603-625 681-703 1149-1171 1222-1244 1289-1311 1402-1424 1471-1493 1513-1535 1542-1559 1606-1625 1700-1722 4dexB(1-45) 3e-15 88.89% 2lcmA(1-28) 1e-06 92.86% 3g43E(2-66) 2e-05 39.47% 2kavA(1-90) 3e-16 23.16% 4dexB(1-45) 2e-15 88.89% 3g43E(2-68) 2e-10 37.18% 2lcmA(1-28) 5e-05 92.86% PF00520(2-198) 2e-30 36.2% PF00520(6-198) 4e-27 36.04% PF00520(2-169) 1e-22 36.92% PF00520(16-197) 3e-18 33.86% PF00520 3e-64 224.0% PF00520 8.2e-59 206.0% PF00520 3.6e-66 230.4% PF00520 5.9e-72 249.6% 1orsC(2-107) 4e-17 14.66% 1orsC(2-108) 5e-08 15.18% 1orsC(2-113) 1e-07 15.13% f.14.1 4e-33 115.1% f.14.1 4.5e-36 125.3% f.14.1 1e-32 113.7% f.14.1 2e-32 112.6%

Sequence

MARFGEAVVARPGSGDGDSDQSRNRQGTPVPASGQAAAYKQTKAQRARTMALYNPIPVRQ
NCFTVNRSLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPM
SRRLEKTEPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHF
NTHVDLRTLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGL
EFYSGKLHRACFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILFAVL
TVFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERER
VENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRT
EAMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRISIRHMVKSQVFYW
IVLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSSF
NCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSM
KSIISLLFLLFLFIVVFALLGMQLFGGRFNFNDGTPSANFDTFPAAIMTVFQILTGEDWN
EVMYNGIRSQGGVSSGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEE
EAFNQKHALQKAKEVSPMSAPNMPSIERDRRRRHHMSMWEPRSSHLRERRRRHHMSVWEQ
RTSQLRKHMQMSSQEALNREEAPTMNPLNPLNPLSSLNPLNAHPSLYRRPRAIEGLALGL
ALEKFEEERISRGGSLKGDGGDRSSALDNQRTPLSLGQREPPWLARPCHGNCDPTQQEAG
GGEAVVTFEDRARHRQSQRRSRHRRVRTEGKESSSASRSRSASQERSLDEAMPTEGEKDH
ELRGNHGAKEPTIQEERAQDLRRTNSLMVSRGSGLAGGLDEADTPLVLPHPELEVGKHVV
LTEQEPEGSSEQALLGNVQLDMGRVISQSEPDLSCITANTDKATTESTSVTVAIPDVDPL
VDSTVVHISNKTDGEASPLKEAEIREDEEEVEKKKQKKEKRETGKAMVPHSSMFIFSTTN
PIRRACHYIVNLRYFEMCILLVIAASSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFE
MVIKMIDQGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVL
RVLRPLKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTD
SSKDTEKECIGNYVDHEKNKMEVKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQH
SVDVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLE
KNERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYY
SAPCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEIILT
DSKLVNTSGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFI
YAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGCEP
DTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDNFEYLTRDSSILGPHH
LDEFVRVWAEYDRAACGRIHYTEMYEMLTLMSPPLGLGKRCPSKVAYKRLVLMNMPVAED
MTVHFTSTLMALIRTALDIKIAKGGADRQQLDSELQKETLAIWPHLSQKMLDLLVPMPKA
SDLTVGKIYAAMMIMDYYKQSKVKKQRQQLEEQKNAPMFQRMEPSSLPQEIIANAKALPY
LQQDPVSGLSGRSGYPSMSPLSPQDIFQLACMDPADDGQFQERQSLEPEVSELKSVQPSN
HGIYLPSDTQEHAGSGRASSMPRLTVDPQVVTDPSSMRRSFSTIRDKRSNSSWLEEFSME
RSSENTYKSRRRSYHSSLRLSAHRLNSDSGHKSDTHRSGGRERGRSKERKHLLSPDVSRC
NSEERGTQADWESPERRQSRSPSEGRSQTPNRQGTGSLSESSIPSVSDTSTPRRSRRQLP
PVPPKPRPLLSYSSLIRHAGSISPPADGSEEGSPLTSQALESNNACLTESSNSPHPQQSQ
HASPQRYISEPYLALHEDSHASDCGEEETLTFEAAVATSLGRSNTIGSAPPLRHSWQMPN
GHYRRRRRGGPGPGMMCGAVNNLLSDTEEDDKC

Region:1-2313
Length:2313aa
Label:Full sequence
Reset:click